CXCL10 and tropical spastic paraparesis: The concentration of the pivotal, pro-inflammatory chemokine, CXCL10, is high in the affected organs of both conditions [35, 36, 95, 96], and CXCL10 levels are correlated with lymphocyte numbers in CSF and BALF in patients with HAM [112] and HAPD [35, 36, 96, 97], respectively.