LDLR and familial hyperaldosteronism: As one of the features of endothelial inflammation is the stimulation of endothelial expression of cell-surface adhesion molecules (CAMs), such as VCAM-1, ICAM-1 and selectins that facilitate leukocyte trafficking in the vascular wall [61], we investigated the pattern of several soluble CAMs in patients with FH and ApoE/LDLR-deficient mice.