CRP and inherited lipid metabolism disorder: Only some minor changes (in the pattern of proteins’ determined) were implemented based on the literature or our previous observations: (1) sVCAM-1 was replaced by sICAM-1 because the latter proved to be more up-regulated in humans in response to hyperlipidaemia [35], (2) CRP level (instead of SAA) was analysed since it is more commonly used in clinical practice demonstrating comparable sensitivity as a measure of inflammation [36] and, finally, (3) alterations in AGT level were evaluated to verify whether dyslipidaemia also initiated profound RAS activation in human samples.