Of note, ferrichrome exerted a greater tumor-inhibitory effect than currently available antitumor drugs, including 5-FU and cisplatin, both in vitro and in a xenograft model, and there were no adverse effects on the biochemical test values of AST, ALT, CRE and Fe in single dose toxicity test, indicating that ferrichrome is a feasible treatment agent for colorectal tumors with a strong anti-tumor effect and broad safety range. Here, GPT is linked to colorectal neoplasm.