For instance, the carcinogenic effect of miR-139-3p in colorectal cancer was mediated by targeting RAB1A [19]; miR-139-3p targeted NOB1 in cervical cancer to regulate cell apoptosis and metastasis [24]; in addition, miR-139-3p targeted MMP11 in bladder cancer [29]. This evidence concerns the gene NOB1 and urinary bladder carcinoma.