SSRP1 and hepatocellular carcinoma: StarBase predicted 8 mRNAs could bind to miR-497-5p [CLIP: strict stringency (> = 5), Degradome: high stringency (> = 3)] By transfecting miR-497-5p mimics into HCC cells, we observed that only SSRP1 was down-regulated (Fig. 4a).