Rehab et al. found that overexpression of FGFR1 was common in malignant bladder cancer, and the sensitivity and specificity of combined FGFR1 and CK20 for the differentiation between MIBC and NMIBC can be as high as 97.5% and 92.5%, respectively [28]. This evidence concerns the gene FGFR1 and urinary bladder cancer.