ATF3 levels were substantially lower in patients with HCC than in healthy individuals of subgroups analyzed based on gender (Fig. 2b), age (Fig. 2c), ethnicity (Fig. 2d), disease stage (Fig. 2e), tumor grade (Fig. 2f), weight (Fig. 2g), and nodal metastasis (Fig. 2h). This evidence concerns the gene ATF3 and neoplasm.