CTTN and breast carcinoma: According to high expression levels of ROCK in lymph node-positive (Fig. 3), ROCK overexpression was significantly associated with ALNM + after adjustments for potential covariates (OR Median-based cutoff = 3.05, 95%CI 1.01–9.18) (Table 2). The overexpressions of CTTN (OR ROC-based cutoff = 4.33, 95%CI 1.64–11.43) and ROCK (OR ROC-based cutoff = 2.92, 95%CI 1.18-7.24) were associated with developed grade II breast carcinoma (Table 3).