CLDN4 and neoplasm: Larger tumor size (> 2 cm) showed higher expression levels of CTTN, CLDN-1, and CLDN-4 than those in smaller tumors (P < 0.05). Overexpressions of ROCK and CLDN-4 were observed in ALNM + tumors more than BrCa counterparts lacking ALNM (P < 0.05).