PCSK1N and Hepatic fibrosis: Spearman rank correlation analysis clearly indicated that Ktrans and Kep were negatively correlated with the stages of liver fibrosis severity (rs = -0.875 for Ktrans and -0.797 for Kep, P < 0.01), while HPI had a high positive correlation with the stages of liver fibrosis (rs = 0.959, P < 0.01).