DSG2 and metastasis: Univariate analysis showed that the CC patients’ OS was associated with DSG2 expression (HR = 0.996, P < 0.001), tumor size (HR = 1.295, P < 0.001), lymph node metastasis (HR = 0.642, P < 0.001), distant metastasis (HR = 3.098, P < 0.001), AJCC stage (HR = 1.331, P < 0.001) and venous invasion (HR = 2.735, P < 0.001).