From the pooled RNA- and miRNA-Seq datasets we identify multiple potential candidate reference genes in cancer exosomes (ARF1, B2M, H3F3AP4, ITM2B, MPP1, OAZ1, PCMTD1, SOD2, SERF2, WIPF1 for mRNA analyses and hsa-miR-125-5p, hsa-miR-192-3p, hsa-miR-4468, hsa-miR-4469, hsa-miR-6731-5p, and hsa-miR-6835-3p for miRNA analyses) (Tables 1 and 2 and Suppl. Here, ITM2B is linked to cancer.