Kruh-Garcia et al. detected twenty proteins from serum in the exosomes of active TB patients, and included multiple peptides from eight proteins (Ag85 b,c, Apa, BfrB, GlcB, HspX, KatG, and Mpt64), in which Ag85b,c, Apa and GlcB proteins are known mycobacterial adhesions [86] and BfrB, HSPx, katG, and MPt64 [92,93] contribute to the intracellular survival of Mtb. Furthermore, Fortune SM and colleagues isolated and evaluated a high concentration of Ag85a, HSPx, and K85R in a mouse model of Mtb infection [94]. Here, ENPEP is linked to tuberculosis.