In multivariate analysis, tumor size, tumor number, presence of microvascular vascular invasion, Nrf2 expressions in the non-tumorous part (HR=1.527, 95% CI = 1.023–2.280, p = 0.038), and Tid1 expression in the non-tumorous part (HR = 0.500, 95% CI = 0.330-0.756, p = 0.001) were independent factors associated with recurrence. Here, NFE2L2 is linked to neoplasm.