SRF and acute kidney injury: The AUCs of SRF mRNA, SRF protein, urinary SRF and serum SRF were 87.9%, 83%, 81.3% and 78.8%, respectively, which were all better than that of Scr (68.8%), which indicated that urinary SRF could be an early diagnostic marker of AKI with better sensitivity and specificity than Scr.