DGCR8 and colon adenocarcinoma: Of these mutations, we found p.E518K in DGCR8 occurring in two of 495 (0.4%) cases of THCA, p.R440Ter in XPO5 in one case of UCEC and one case of SKCM, and p.D1151E in DROSHA in one case of COAD (Supplementary Figure S3).