Of the indel hotspots in XPO5 and TARBP2 detected previously in colon, gastric, and endometrial tumors with MSI (67,68), we detected only two cases of the C insertion in the poly-C track (p.M145HfsTer13) in TARBP2: one in UCEC and one in STAD (both cancers often characterized by MSI). Here, XPO5 is linked to cancer.