Moreover, we identified the IFNγ-CXCL10 axis as being one of the drivers of TCB-mediated T cell infiltration in tumors, whereby IFNγ released by activated T cells induces CXCL10 secretion, which in turns attracts CXCR3-expressing T cells into the tumor sites. This evidence concerns the gene CXCL10 and neoplasm.