Despite peculiar features of target cells such as expression of CD20, ICAM-1 and LFA-1 might explain difference in killing between WSU and OCI-Ly18, they do not suffice to explain heterogeneity observed in other human DLBCL cell lines (S1f and S1g Fig), leaving the stability of synapse formation the main read-out correlating with efficiency. The gene discussed is ICAM1; the disease is diffuse large B-cell lymphoma.