Due to its role in neuronal stem cell proliferation and the increasing significance of cancer stem cells, Banasavadi-Siddegowda et al. investigated the differential effects of PRMT5 silencing through pooled siRNA in stem-like and differentiated glioblastoma cells (Banasavadi-Siddegowda et al. 2017). Here, PRMT5 is linked to glioblastoma.