Univariate analysis showed that CEA and SIR, including NLR, PLR and LMR, were closely related to the prognosis in the training set (all p < 0.05, Table 1), and the other relevant clinicopathological data included age, tumor size, differentiation degree, vascular invasion, pTNM stage, and ALB content (all p < 0.05, Table 1). This evidence concerns the gene CEACAM5 and neoplasm.