Our work did not analyze survival rates and prognoses owing to the unavailability of clinical data; however, pan-cancer analysis of 14 cancers in TCGA showed that hypermethylated and downregulated MAP4K1, PRKCB, IKZF1, MAP4K1, and SHISA3 were associated with longer overall survival in HNSC and other cancers. Here, SHISA3 is linked to cancer.