The IHC map of CCRGs is shown in Figure 7 and confirmed that CCNE2, CCNB1, CCNB2, TTK, CDC20 and PTTG1 were significantly overexpressed in BC tissues compared with normal mammary tissues (p<0.05); however, BUB1B was not confirmed to be significantly overexpressed in BC tissues due to the lack of data available in the Human Protein Atlas. This evidence concerns the gene BUB1B and breast cancer.