Gene expression analysis of glioma and glioblastoma cells revealed that Meis2 was one of the differentially expressed genes and it could be a prognostic biomarker for glioma and glioblastoma development, in addition to with other genes, including Meox2, Pitx2, Nr2e1, and Tfap2B (Vastrad et al., 2017). The gene discussed is PITX2; the disease is central nervous system cancer.