CD4 and neoplasm: This GEP is characteristic of immune-reactive tumours with prolonged survival and response to ICIs.48,49 A similar GEP has also been associated with high tumour T-cell infiltration in OC patients.50,51 In line with the transcriptomic data, FC analysis of tumour infiltrates revealed a significantly higher frequency of CD8 and CD4 T cells in those patients who rendered TR TILs.