Specifically, LOX-1 is upregulated in 57% of bladder and cervix cancer cells, 11% of mammary gland cancer cells, 10% of lung cancer cells, and in 20% of colorectal cancer (CRC) cells, as reported in the meta-analysis of gene expression profiles of about 950 cancer cell lines [22]. The gene discussed is OLR1; the disease is colorectal carcinoma.