MANBA and type 2 diabetes mellitus: Two missense variants within MANBA (mannosidase, beta A, lysosomal) are in LD (1000 Genomes Project, EUR populations) with our FG lead variant rs223486 [e.g. rs2866413 (p.Thr701Met, r2 = 0.36) and rs227368 (p.Val253Leu, r2 = 0.58)] and have suggestive effects on FG (Psex-combined_rs2866413 = 8.7 × 10−5, Psex-combined_rs227368 = 6.4 × 10−4) in the current dataset, but no nominal effect on T2D risk in European ancestry populations (Prs2866413 = 8.8 × 10−4, Prs227368 = 4.1 × 10−5).