MANBA and ulcerative colitis: Conversely, the rs223486 association with FG was not explained by rs3774959 variant at MANBA previously associated with ulcerative colitis (rs223486, Pconditional_rs3774959 = 9.6 × 10−8, r2EUR = 0.12)32 (Supplementary Fig. 1f–h), suggesting a genetic relationship between glucose homeostasis and neurodegeneration.