In the sex-combined meta-analyses that included four additional family-based studies compared to the sex-dimorphic meta-analyses, we identified genome-wide significant associations for FG at six novel loci (ZBTB38, MANBA/UBE2D3, RGS17, PDE6C, IGF1R, and NFATC3) and one established T2D locus (HMG20A, same variant)24 (Table 1, Fig. 1, Supplementary Fig. 2). Here, PDE6C is linked to type 2 diabetes mellitus.