Among the 162 DAM genes, we found only 8 genes were deregulated in AD precuneus, and unexpectedly, all of them (APBB2, ARAP2, DHCR7, ENPP2, MYO1E, CDS22, KCNJ2, and SLC44A1) were downregulated (Fig. 5b). Here, ARAP2 is linked to Alzheimer disease.