Half of the sample suffered from chronic diabetes complications related with the eye (50.0%: mostly retinopathy), atherosclerotic disease (47.8%: mostly peripheral artery disease) or nephropathy (47.4%: mean creatinine: 2.58 mg/dl; mean eGFR: 41.15 ml/min/1.73m2; mean eGFR basal: 47.60 ml/min/1.73m2; mean albumin: 248.42 μg/mg; median proteinuria: 344.00 mg). The gene discussed is ALB; the disease is retinal disorder.