Previously, with the GEPIA database (http://gepia.cancer-pku.cn/), we found that the expression level of GAP43 was significantly downregulated in colorectal cancer tissues (normal versus cancer tissues), including the colon adenocarcinoma (COAD) and rectal adenocarcinoma (READ) (Supplementary Fig. S1a). The gene discussed is GAP43; the disease is colon adenocarcinoma.