The gene expression level of NCOA4 was significantly lower in tumor samples in comparison to normal tissues of ccRCC in TCGA database(p = 7.337e-2) (Fig. 1), which was also validated in GEO database (p = 4.696e-05, 0.018) (Fig. 2). The gene discussed is NCOA4; the disease is nonpapillary renal cell carcinoma.