The results displayed that the expression level of NCOA4 had obviously positive correlation with infiltrating levels of B cells (r = 0.304, P = 2.79e-11), CD8+ T cells (r = 0.186, P = 9.32e-05), macrophages (r = 0.477, P = 8.65e-27), neutrophils (r = 0.29, P = 2.57e-10), and dendritic cells (r = 0.326, P = 9.65e-13) in ccRCC, but no association with tumor purity and CD4+ T cells. The gene discussed is CD8A; the disease is nonpapillary renal cell carcinoma.