Other studies have shown that, CA125 was associated with the R0 resection rate [13], recurrence, peritoneal dissemination [14] and OS in unresectable advanced or recurrent GC patients [15]; CA199 was related to pN [7, 16–18] and pTNM stage [17]; and CA724 was related to the pathological stage and had a good diagnostic value for gastric cancer [19]. The gene discussed is MUC16; the disease is gastric cancer.