ACHE and early-onset autosomal dominant Alzheimer disease: The alkaloid galanthamine is a long-acting, selective, reversible, and competitive acetylcholinesterase (AChE) inhibitor used for the treatment of Alzheimers disease and is still obtained from plants, mainly from Leucojum aestivum (summer snowflake) and Narcissus (daffodils) in Europe, Lycoris radiata in China, and Ungernia victoris in Tadzhikistan and Uzbekistan [6,7].