SLC7A5 and cancer: LAT1 mediates the uptake of neutral EAAs (leucine, isoleucine, phenylalanine, methionine, histidine, tryptophan, valine, and tyrosine) into cancer cells [69,70] in exchange for the efflux of intracellular substrates (EAAs and/or glutamine) [71,72], thus serving as an amino acid antiporter.