EpCAM, a functional marker of ovarian cancer stem cells, forms a complex with amino acid transporters including LAT1 and CD98hc [86,87,88], and the expression level of LAT1 is positively correlated with poor clinical outcomes in ovarian cancer, renal cell carcinoma, and pancreatic ductal adenocarcinoma [89,90,91]. The gene discussed is SLC7A5; the disease is hereditary clear cell renal cell carcinoma.