Similarly, myeloid-derived suppressor cells have been recently shown to be expanded in the blood and marrow of MDS patients, contributing to ineffective granulopoiesis through the production of inflammatory molecules, such as transforming growth factor-beta (TGF-β), nitric oxide, IL-10, and arginase, impairing T-cell surveillance on MDS progression [73,74,75]. This evidence concerns the gene IL10 and myelodysplastic syndrome.