For instance, IL-10 and TGF-β have been implicated in the maintenance of TRM populations in tumours [222,223,224], while the induction of TCF7 gene expression (a key transcription factor that regulates T cell stemness and longevity) has also been shown to be controlled by a core transcription factor group that includes the master Th2 regulator, GATA3 [225]. Here, IL10 is linked to neoplasm.