PDHA1 and hyperinsulinemic hypoglycemia, familial, 4: The findings presented here (Figure 7) show that the elimination of PDC activity in otherwise normal mouse liver by Pdha1 gene deletion (without involving any cancer‐mediated modulators described above) is sufficient to induce Warburg‐type respiration as a result of PDC deficiency (Jackson et al., 2017; Reznik et al., 2017).