RT-qPCR and immunohistochemistry (IHC) results showed that the expression levels of K10, filaggrin, and AQP4 in the irradiated group and AD-NC + irradiated group were significantly higher than those in the NC group and AD-miR-24-3p + irradiated group, of which AD-miR-24-3p + irradiated group was higher than NC group (Fig. 3a, b). The gene discussed is FLG; the disease is Alzheimer disease.