In the first analysis, they examined whether a loss-of-function coding single nucleotide polymorphism (SNP) in the endothelial lipase gene (LIPG rs61755018, Asn396Ser) would predict MI risk in a combined population of subjects with MI (n = 20,913 cases) or controls (n = 95,407). The gene discussed is LIPG; the disease is myocardial infarction.