TXNRD1 and colorectal carcinoma: Based on evidence from previous studies, cancer promotion by FTX may involve the following mechanisms: FTX significantly promotes the proliferation and invasion of glioma cells by negatively regulating miR-342-3p [16]; FTX exerts its oncogenic role in OSC via up-regulating the expression of TXNRD1 through sponging miR-320a [28]; FTX promotes proliferation and invasion of gastric cancer via the miR-144/ZFX axis [29]; FTX functions as an oncogene to contribute to CRC progression by regulating the miR-192-5p/EIF5A2 axis [9].