For example, in the meta-analysis investigating the lncRNA GHET-1, GHET-1 expression was closely correlated with tumor size, lymph node metastasis, distant metastasis and TNM stage, and increased GHET-1 expression may be a potential prognostic biomarker in human cancers including HCC, GC,OSC, breast cancer, baldder cancer, cervical cancer, NSCLC, and esophageal cancer (ESCC) [30]. This evidence concerns the gene GHET1 and hepatocellular carcinoma.