Genes involved in extracellular matrix and cell-adhesion were also modulated, particularly during fatal Lassa fever (NID1, TIMP3, ITGA11, TGM2, MMP8/9, OLFM4, PCDH20, and CADM3), as well as some others involved in coagulation (SERPIN, TFPI2) and apoptosis (CLU, BCL2L14). This evidence concerns the gene MMP8 and Lassa fever.