Emerging evidence has suggested that ferroptosis could be discovered in the neuronal cell death associated with various neurological diseases, such as hemorrhagic stroke, ischemic stroke, Parkinson’s disease and Huntington’s disease, accompanied by lipid peroxidation, mitochondrial dysfunction and reduction of glutathione peroxidase 4 (GPX4) [12–16]. Here, GPX4 is linked to Parkinson disease.