Here, also, we found that skin cancer cell lines were significantly more dependent on MAPK1 (t = 16.5, p = 1.33 × 10−55; Fig. 4f) and BRAF (t = 17.9, p = 1.6 × 10−63; Fig. 4g) expression than were other cell lines. This evidence concerns the gene BRAF and skin neoplasm.