In contrast, genes involved in stimulating desaturation of FA (Scd1, Scd2 and Fads1, Fads2) were expressed at lower levels in HF/C M than F (Fig. 3f and Supplementary Fig. S3a), which was in accordance with higher levels of VLCTG and SFA, as well as lower levels of MUFA in HF/C M than in F. Interestingly, M and F showed opposite response to MO in the expression levels of key genes of the FA synthesis and inflammatory pathways (Fig. 3g and Supplementary Fig. S3b–e). The gene discussed is FADS2; the disease is hydrops fetalis.