The expressions of both Fis1 and Txn1 were significantly decreased in WT-STZ mice, but not in miR-379KO-STZ mice, compared to their respective nondiabetic controls at 6 and 24 weeks after diabetes (for Fis1) and at 1 week post diabetes for Txn1 (Fig. 7h, i). Here, TXN is linked to diabetes mellitus.