Because excess DC activation is suggested in many autoimmune and allergic diseases, and possible associations of single-nucleotide polymorphisms of TARM1 with RA and uveitis are suggested in published data (rs654765, rs112143130, rs73060651, rs112227086 and rs61416627; P < 0.05)48, our observations suggest that TARM1 is a good target for the development of new drugs to treat such diseases. Here, TARM1 is linked to uveitis.