To assess this hypothesis, we generated xenograft tumors using the KIFC1-WT, KIFC1-S26A, and KIFC1-S26D rescued MDA-MB-231 cell lines, and determined the tumor growth and recurrence in the presence of etoposide alone and in combination with PBS, VE-822, or CW069 (Fig. 8a). Here, KIFC1 is linked to neoplasm.