IL1B and congenital rubella syndrome: Remarkably, the increased serum levels of cytokines after CAR T infusion, including human IL-1β (hIL-1β), hIL-8, hTNF-α, hIFN-γ, and mIL-1β, mIL-6 [8, 9], could be broadly reduced by THZ1 to alleviate the severity of CRS (Fig. 6c).