REN and autosomal dominant medullary cystic kidney disease with or without hyperuricemia: Uromodulin (UMOD), Mucin-1 (MUC1), renin (REN), Hepatocyte nuclear factor 1 beta (HNF1β) and alpha subunit of the endoplasmic reticular membrane translocon (SEC61A1) are the genes responsible for ADTKD [1, 2].