NLRP3 and Muckle-Wells syndrome: A spectrum of autosomal-dominant autoinflammatory syndromes of different severities, including Muckle-Wells syndrome (MWS), familial cold autoinflammatory syndromes 1 and 2 (FCAS1, FCAS2), and chronic infantile neurologic cutaneous and articular (CINCA) syndrome, are related to cryopyrin.