Third, from our in silico gene deletion analysis, we identified Sterol O-Acyltransferase 1 (SOAT1), methylmalonyl-CoA mutase (MUT), and isozymes of succinate dehydrogenase (SDHA, SDHB, SDHC, and SDHD) as having a significant effect (p-value < 0.05) in cancer as compared to normal samples. The gene discussed is SDHC; the disease is cancer.