In this work, a screening of the Ph.D.-C7C phage peptide library was carried out to obtain tumor-targeting peptides to U-87 MG tumor cells with the phenotype of tumor stem cells (CD44+/CD133+), as well as a comparative analysis of the distribution in the body of mice and the specificity of the interaction with U87 MG tumor of bacteriophages displaying tumor-targeting peptides selected during biopanning of various peptide libraries in different selection systems. The gene discussed is CD44; the disease is neoplasm.