As characterized by matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) analysis, MHC-I, together with heat shock proteins HSC70 and HSP90, annexins, PV-1 and developmental endothelial locus-1 (DEL-1), were found to be present in exosomes derived from human mesothelioma cells [283]. The gene discussed is EDIL3; the disease is mesothelioma.